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A nephron consists of


A) a renal corpuscle and a renal tubule.
B) an afferent and efferent arteriole.
C) a cortex and a medulla.
D) a bladder and a ureter.

E) B) and C)
F) A) and C)

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Karl is around 60 years old. He begins to notice that he can't control his bladder as efficiently lately. Leakage of urine is starting to become common. He might have


A) enlarged kidneys.
B) an enlarged prostate.
C) less vitamin D.
D) damaged nephrons.

E) C) and D)
F) None of the above

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The efferent arteriole supplies blood to the capillary of the glomerulus.

A) True
B) False

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The juxtaglomerular apparatus regulates the filtration rate by ________.


A) vasodilation of the peritubular capillaries
B) vasoconstriction of the peritubular capillaries
C) renin-angiotensin II vasoconstricting both the afferent and efferent arterioles
D) increasing osmotic pressure in the glomerular capsule

E) B) and D)
F) B) and C)

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During urine formation, some substances move from the plasma in the peritubular capillary into the renal tubule by the process called ________.

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Select the sequence that indicates the parts of a renal tubule in the correct sequence from beginning to end.


A) Proximal convoluted tubule, ascending limb of nephron loop, descending limb of nephron loop, distal convoluted tubule
B) Distal convoluted tubule, ascending limb of nephron loop, descending limb of nephron loop, proximal convoluted tubule
C) Proximal convoluted tubule, descending limb of nephron loop, ascending limb of nephron loop, distal convoluted tubule
D) Collecting duct, proximal convoluted tubule, descending limb of nephron loop, ascending limb of nephron loop, distal convoluted tubule

E) All of the above
F) B) and D)

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Water is reabsorbed throughout most of the renal tubule by the process of ________.

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The detrusor muscle is in the


A) ureter.
B) urethra.
C) kidneys.
D) urinary bladder.

E) B) and D)
F) C) and D)

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Which choice describes the countercurrent mechanism of the nephron loop?


A) Water moves out of the ascending limb; sodium moves into the ascending limb
B) Water moves into the ascending limb; sodium moves out of the ascending limb
C) Water moves out of the descending limb; sodium moves out of the ascending limb
D) Water moves into the descending limb; sodium moves out of the descending limb

E) B) and D)
F) None of the above

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At rest, the kidneys receive about a quarter of the blood coming from the heart.

A) True
B) False

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Sympathetic nerve impulses usually cause proportional degrees of vasodilation in the afferent and efferent arterioles.

A) True
B) False

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If the osmotic pressure of the blood plasma is decreased, the glomerular filtration rate is increased.

A) True
B) False

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The organs of the urinary system are


A) the renal cortex, renal pelvis, and renal medulla.
B) the glomerular capsule, proximal convoluted tubule, the nephron loop, distal convoluted tubule, and the collecting duct.
C) a kidney, a ureter, and paired bladders and urethras.
D) paired kidneys, paired ureters, a bladder and a urethra.

E) A) and B)
F) C) and D)

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Michael is 26 years old. He becomes dehydrated after a long run if he has not drunk enough. His infant son Sean, however, becomes dehydrated fairly frequently. This difference in susceptibility to dehydration is because


A) adults drink more liquid.
B) infants grow rapidly.
C) infant kidneys are less able to conserve water.
D) the infant thirst mechanism is underdeveloped.

E) None of the above
F) A) and C)

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During development, the embryo is injected with anti-VEGF (which negates VEGF functions) . Which of the following effects will occur? 


A) Mesangial cells will be hyper-stimulated to specialize because VEGF is inhibited, so glomerular filtration rate will be highly decreased.
B) VEGF won't stimulate growth of the proximal convoluted tubule.
C) The parietal layer of the glomerular capsule will not be formed, as the squamous epithelium won't be attracted to VEGF.
D) Platelet-derived growth factor (PDGF) will be mass-produced and cause unchecked growth and development of mesangial cells.

E) A) and B)
F) A) and C)

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Kidney shrinkage with age is due to


A) spooling of collecting ducts.
B) loss of glomeruli.
C) merging of proximal and distal convoluted tubules.
D) proliferating nephron loops.

E) A) and C)
F) C) and D)

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Hemodialysis involves


A) an artificial kidney.
B) an artificial liver.
C) a kidney transplant.
D) a bone marrow transplant.

E) A) and B)
F) A) and C)

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In which of the following regions of the nephron is water actively transported?


A) Proximal convoluted tubule
B) Descending limb of the nephron loop
C) Peritubular capillaries
D) Collecting duct

E) A) and B)
F) A) and C)

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Liam is a body builder and frequently consumes protein powder as part of his fitness regimen. He consumes more protein than his body actually uses. What happens to the excess protein?


A) It is filtered through the glomerular capillary into the glomerular capsule and into the nephron, where it is finally excreted in the urine.
B) It is broken down into urea by the liver, which is then filtered into the glomerular capsule and also secreted elsewhere in the nephron.
C) The large proteins are secreted into the distal convoluted tubule by tubular secretion.
D) It is stored in adipocytes after being converted into fats.

E) B) and C)
F) C) and D)

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Active transport mechanisms have limited transport capacities because the renal tubule is not very permeable to molecules.

A) True
B) False

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